1. St. John’s wort
A 2016 systematic reviewTrusted Source found that St. John’s wort was more effective than a placebo for treating mild to moderate depression and worked almost as well as antidepressant medications.
Practitioners of Chinese medicine have used ginseng for thousands of years to help people improve mental clarity and energy and reduce the effects of stress.
Some people associate these properties of ginseng with potential solutions for the low energy and motivation that can occur with depression.
The results show that chamomile produced more significant relief from depressive symptoms than a placebo. However, further studies are necessary to confirm the health benefits of chamomile in treating depressive symptoms.
Lavender oil is a popular essential oil. People typically use lavender oil for relaxation and reducing anxiety and mood disturbances.
Some studies cite using saffron as a safe and effective measure for controlling the symptoms of depression, such as this non-systematic review from 2018Trusted Source.
7. Omega-3 fatty acids
In a 2015 systematic reviewTrusted Source, researchers concluded that omega-3 fatty acid supplements are not useful across the board as a depression treatment.
While the study authors reported no serious side effects from the supplement, they also advised that it would only be an effective measure in treatment for depression that was due to omega-3 deficiency.
Also known as 5-hydroxytryptophan, this supplement may be useful in regulating and improving levels of serotonin in the brain. Serotonin is the neurotransmitter that affects a person’s mood.
5-HTP has undergone a number of animal studies, and some, such as this review from 2016Trusted Source, cite its potential as an antidepressant therapy. However, evidence of its effects in human subjects is limited.
SAMe is short for S-adenosyl methionine. It is a synthetic form of a chemical that occurs naturally in the body.